Multifocal osteolysis with nephropathy.

Multifocal osteolysis with nephropathy.

A patient with progressive osteolysis of the carpal and tarsal bones with glomerulonephritis of unusual severity is described. There was a notable absence of osteodystrophy in this and other reported cases who had chronic renal failure.

Idiopathic multicentric osteolysis with acro-osteolysis. A case report.

We report a case of multicentric massive osteolysis. A 52-year-old woman presented with a three-year history of progressive deformities of the hands. She had osteolytic lesions of the metacarpals and metatarsals, and resorption of the terminal phalanges. During follow-up over four years osteolysis spread to affect the ribs, clavicles, mandible, and long bones. There was no family history of any...

Massive osteolysis.

Mandibular Involvement in Recurrent Multifocal Osteomyelitis Associated with SAPHO Syndrome

Introduction: SAPHO syndrome is defined as the association of a group of rare sterile osteoarticular disorders and inflammatory skin diseases whose etiology, although not yet determined, probably involves genetic, immunological and infectious mechanisms. The recurrent multifocal osteomyelitis, an inflammatory disease, can be associated with this syndrome even as a single event.  Case Report:...

RANKL links arterial calcification with osteolysis.

Vascular calcification is a pathological sequence of events that has similarities to the normal physiological process of osteogenesis.1,2 It is thought to result from an imbalance in both local and systemic inhibitors and promoters,3,4 which occurs as a consequence of chronic inflammation, hyperleptinemia, and a deregulation of various bone-regulating proteins. It is common in patients with dia...